Product Evaluation

The Special Pathogens Laboratory has been an active research partner with industry in evaluating new technologies for the detection, treatment and control of Legionella and other waterborne pathogens.  Our approach includes a step-wise evaluation criteria for determining the efficacy of disinfection methods.  This was described in a 2003 report entitled "Experiences of the First 16 Hospitals using Copper-silver Ionization: Implications for the Evaluation of Other Disinfection Modalities". 

The results of these studies have been presented at national meetings and published in peer-reviewed journals.  Examples are listed below:

Zhang Z, McCann C, Stout JE, et al.  Prospective study of the safety and efficacy of chlorine dioxide for Legionella control in a hospital water system.  Infect. Control Hosp Epid.  2007; Submitted for Publication.

 Sheffer PJ, Stout JE, Wagener MM, Muder RR.  Efficacy of new point-of-use filter for preventing exposure to Legionella and waterborne bacteria.  Am. J. Infect. Control. 2005; 33(5) Suppl. 1: S20-S25.

Stout, JE, Sens K, Mietzner S, Obman A, Yu, VL.  Comparative activity of quinolones, macrolides, and ketolides against Legionella species using in vitro broth dilution and intracellular susceptibility testing. Int J Antimicrob Agents 2005; 25:302-307. 

Sidari FP, Stout JE, VanBriesen JM, Bowman AM, Grubb D, Neuner A, Wagener MM,  Yu VL.  Chlorine dioxide as a disinfection method for Legionella control.  J Amer Water Works Assoc. 2004; 96: 111-119.

Stout JE, Yu, VL.  Experience of the first 16 hospitals using copper-silver ionizaton for Legionella control: implications for the evaluation of other disinfection modalities.  Infection Control Hosp. Epid. 2003; 24(8): 563-568.  

Yang G, Stout JE,  Zhou P, Lin YE, Vidic R.  Efficacy of DBNPA against Legionella pneumophila: experimental results in a model water system (Abstract 4432).  ASHRAE, Atlanta GA, January 27-31, 2001. 

Mietzner SM, Stout JE, Shannon JL, Yu VL, Wareing DR. Evaluation of the Dynal Biotech Legionella immunomagnetic seperation method versus conventional culture for the isolation of Legionella pneumophilia serogroup 1 from water samples. In Cianciotto NP, Kwaik YA,Edelstein PH, Fields BS, Geary DF, Harrison TG, Joseph CA, Ratcliff RM, Stout JE, and Swanson MS (eds.), Legionella State Of The Art 30 Years After Its Recognition. p. 449-452. American Society for Microbiology, Washington, DC.